Supramolecular chemistry: analysing a host-guest assembly

In kJ/mol: metal-ligand coordination $40$ to $400$; hydrogen bond $4$ to $120$; ion-dipole $50$ to $200$; hydrophobic effect $1$ to $40$ (entropic); π-π stacking $2$ to $10$; van der Waals $0.1$ to $5$. The first two are strongly directional. Taken one at a time they are weak; their number and their cooperativity hold the assembly together.